2024 Qsymia long term side effects

Aug 22, 2021 · Indeed, in the wake of the fen-phen problems, the FDA rejected all drug company efforts to win approval for new weight-loss drugs between 1999 and 2012. Since then, it has approved four drugs for ... . How much did planet fitness pay for new year

Dec. 4, 2019 — A new study finds the only reliable way to measure exposure to radon gas is with a long-term testing kit, 90 or more days. Researchers placed two test kits, a short term (five-day ...Taking this medication late in the day may cause trouble sleeping ( insomnia ). Swallow the capsules whole. Do not crush or chew the capsules. Doing so can release all of the drug at once,...Common side effects include tingling, dizziness, trouble sleeping, and constipation. Serious side effects may include suicide, abuse. Use is not recommended during pregnancy. Phentermine is a stimulant and appetite suppressant. Topiramate is an anticonvulsant that has weight loss side effects.I have been on Qsymia since 2016, I lost 45 lbs and have kept it off since then. I weigh 163 and wish I could lose at least 8 more lbs, but I have plateaued. I have been taking it this long and had no side effects only at the first 2 weeks I had the tingling sensation on my legs.The latest weight loss drugs work in a new way to help you shed pounds with minimal side effects. Learn how they do it and why you take them long term. ... (Qsymia®): This medication also ...1. In 2012, a new medication called Qsymia (with both Adipex and Topamax components) became available for weight loss. It was the first FDA approved weight loss drug in its class. The weight loss pill is a combination of 2 existing drugs: phentermine and topiramate. This combination has been shown to be a good tool for weight loss in addition ...On July 17, 2012, the FDA approved a tablet combining phentermine plus extended-release topiramate (Qsymia, Vivus) for weight loss. Phentermine has been used for weight loss, and topiramate is an antiepileptic agent that has been commonly associated with weight loss as a side effect. The doses approved for weight reduction are lower than either ...Aug 4, 2022 · Less common. Chest discomfort. decreased urine. dry mouth. fast, irregular, pounding, or racing heartbeat or pulse. loss of appetite. mood changes. muscle pain or cramps. nausea or vomiting. numbness or tingling in the hands, feet, or lips. seizures. The latest weight loss drugs work in a new way to help you shed pounds with minimal side effects. Learn how they do it and why you take them long term. ... (Qsymia®): This medication also ...This includes isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline. Very high blood pressure may happen. If you are taking any of these drugs: Linezolid or methylene blue. If you are pregnant or may be pregnant. Do not take this drug if you are pregnant. If you are breast-feeding.Saxenda Side Effects: Long-term use of Saxenda can lead to dangerous effects, such as suicidal thoughts, impaired kidney function, pancreatitis, gallbladder disease, and increased heart rate. Short-Term Diet Pills Side Effects: Due to amphetamine-type effects, medications approved for short-term use can cause elevated heart rate and blood ...Jan 6, 2021 · During the last few decades, some anti-obesity drugs were used to treat morbid obesity; however, many of them were removed from the market owing to long-term side effects, particularly cardiovascular issues . Since then, anti-obesity drug development process focusses on both weight loss efficacy and cardiovascular safety. Feb 1, 2023 · Phentermine is used as part of a short-term plan, along with a low calorie diet, for weight reduction. It is used in obese patients who have not been able to lose weight with diet and exercise alone. Phentermine belongs to the group of medicines known as appetite suppressants. This medicine is available only with your doctor's prescription. Summary. Commonly reported side effects of orlistat include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules.Dec. 4, 2019 — A new study finds the only reliable way to measure exposure to radon gas is with a long-term testing kit, 90 or more days. Researchers placed two test kits, a short term (five-day ...I have been on Qsymia since 2016, I lost 45 lbs and have kept it off since then. I weigh 163 and wish I could lose at least 8 more lbs, but I have plateaued. I have been taking it this long and had no side effects only at the first 2 weeks I had the tingling sensation on my legs.Aug 17, 2019 · 1. In 2012, a new medication called Qsymia (with both Adipex and Topamax components) became available for weight loss. It was the first FDA approved weight loss drug in its class. The weight loss pill is a combination of 2 existing drugs: phentermine and topiramate. This combination has been shown to be a good tool for weight loss in addition ... Aug 17, 2019 · 1. In 2012, a new medication called Qsymia (with both Adipex and Topamax components) became available for weight loss. It was the first FDA approved weight loss drug in its class. The weight loss pill is a combination of 2 existing drugs: phentermine and topiramate. This combination has been shown to be a good tool for weight loss in addition ... Nov 15, 2022 · diarrhea. dry mouth and tongue. bad taste in your mouth. constipation*. headaches*. mild allergic reaction *†. * To learn more about this side effect, see the “Side effects explained ... Ozempic, a medication used in type 2 diabetes, is currently under review by the FDA to be approved for weight loss in overweight or obese adults. Phentermine may be a more accessible option to help you lose weight, but it should only be used for a few weeks. Both Ozempic and phentermine can help to curb your appetite so that you eat fewer ...On July 17, 2012, the FDA approved a tablet combining phentermine plus extended-release topiramate (Qsymia, Vivus) for weight loss. Phentermine has been used for weight loss, and topiramate is an antiepileptic agent that has been commonly associated with weight loss as a side effect. The doses approved for weight reduction are lower than either ...Symptoms of severe phentermine side effects include ( 3 , 4 ): Chest pain. Pounding or irregular heartbeat, or fluttering in your chest. Lightheadedness or faintness. Shortness of breath, even with only mild exertion. Swelling in your legs, ankles, or feet (edema) Slurred speech or weakness on one side of your body.or short-term obesity treatment in conjunction with lifestyle modifications, but is commonly used chronically. Topiramate, approved for treating epilepsy and preventing migraines, also induces weight loss. A single-dose combination of low-dose phentermine and topiramate extended-release was recently approved by the United States Food and Drug Administration as an adjunct to lifestyle ...After stopping phentermine, some people experience feelings of weariness and fatigue due to the sudden lack of chemical stimulation. If you are tired after stopping phentermine, take care to: Get enough sleep. Fuel your body with healthy foods: avoid high-fat, high-carb, and high-sugar goods that may worsen fatigue. Stay lightly active.Jun 17, 2022 · The options have short-term side effects and long-term risks. However, when other weight loss medications and diets have not produced adequate results, doctors may consider surgery. Uses. This medication is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who ...Apr 26, 2023 · The combination of phentermine and extended-release topiramate (Qsymia) was approved by the FDA in July 2012 as an adjunct to a reduced-calorie diet and exercise for long-term weight management in individuals with an initial BMI of 30 kg/m 2 or higher (obese) or 27 kg/m 2 or higher (overweight) with at least one weight-related comorbid ... Jan 11, 2023 · In general, Phentermine chemicals do have side effects on long-term treatment. One of the most common side effects is dry mouth. Aside from this, you may also experience nervousness or jitteriness ... Serious side effects vary by drug but can include depression, heart palpitations, fast or irregular heartbeat, increased blood pressure, dizziness, tremors, chest pain, and difficulty breathing ...Feb 1, 2023 · Phentermine is used as part of a short-term plan, along with a low calorie diet, for weight reduction. It is used in obese patients who have not been able to lose weight with diet and exercise alone. Phentermine belongs to the group of medicines known as appetite suppressants. This medicine is available only with your doctor's prescription. Oct 27, 2021 · Introduction. The worldwide prevalence of overweight and obesity, defined as having a body mass index (BMI) between 25.0–29.9 kg/m 2 and ≥30.0 kg/m 2, 1 has almost tripled since the 1970s, with nearly 40% of adults being overweight and 13% obese, and these numbers have been steadily increasing. 2 Patients with obesity are at an increased risk of developing comorbidities such as ... Introduction. The worldwide prevalence of overweight and obesity, defined as having a body mass index (BMI) between 25.0–29.9 kg/m 2 and ≥30.0 kg/m 2, 1 has almost tripled since the 1970s, with nearly 40% of adults being overweight and 13% obese, and these numbers have been steadily increasing. 2 Patients with obesity are at an increased risk of developing comorbidities such as ...May 3, 2023 · 1. Nausea and vomiting. Nausea is the most common semaglutide side effect. Up to 20% of people taking it for Type 2 diabetes reported nausea in clinical trials. Nausea is even more common if you’re taking the higher-dose version for weight loss. Vomiting tends to be less common than nausea. In clinical studies, phentermine-topiramate reduced body weight by 8.6% to 9.4% more than placebo using a conservative ITT analysis.108. Phentermine-topiramate carries risks of several serious side effects. Notably, topiramate is a recognized teratogen, at least at the higher doses used for the treatment of epilepsy.Approved for long-term use? Yes. Qsymia has much lower amounts of phentermine and topiramate than when these drugs are given alone. Side effects: The most common side effects are tingling hands ...This combination consists of fixed lower doses of phentermine and topiramate (3.75/23, 7/46, 11.25/69 and 15/92 mg) and is available in capsules under the brand name Qsymia. Common side effects of phentermine include nervousness, excitability, insomnia, headache, dry mouth, sweating, tachycardia, palpitations, nausea, constipation, and thirst.What Is Wegovy? Wegovy (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e ...Common Side Effects of Weight Loss Drugs. Increased blood pressure and heart rate, insomnia, nervousness, restlessness, dependence, abuse or withdrawal may occur with long-term use. When given as a single agent, phentermine is not implicated in valvular heart disease; avoid use at bedtime.Oct 27, 2021 · Introduction. The worldwide prevalence of overweight and obesity, defined as having a body mass index (BMI) between 25.0–29.9 kg/m 2 and ≥30.0 kg/m 2, 1 has almost tripled since the 1970s, with nearly 40% of adults being overweight and 13% obese, and these numbers have been steadily increasing. 2 Patients with obesity are at an increased risk of developing comorbidities such as ... At 6 months, a year, and 2 years after starting phentermine, weight loss was clinically significantly greater among people who used the medication longer-term (more than a year) or medium-term (more than112 days but less than a year) than in people who used it for only 3 months.trouble sleeping (insomnia) new or worse irritability acting aggressive, being angry, or violent acting on dangerous impulses an extreme increase in activity and talking (mania) other unusual changes in behavior or mood Serious eye problems which include: Qsymia's results have been clinically tested in two long-term studies with ... QSYMIA CAN CAUSE SERIOUS SIDE EFFECTS, INCLUDING: Birth defects (cleft lip/cleft palate). If you take Qsymia during ...The table below lists prescription drugs approved by the FDA for weight loss. The FDA has approved five of these drugs—orlistat (Xenical, Alli), phentermine-topiramate (Qsymia), naltrexone-bupropion (Contrave), liraglutide (Saxenda), and semaglutide (Wegovy)—for long-term use.In clinical studies, phentermine-topiramate reduced body weight by 8.6% to 9.4% more than placebo using a conservative ITT analysis.108. Phentermine-topiramate carries risks of several serious side effects. Notably, topiramate is a recognized teratogen, at least at the higher doses used for the treatment of epilepsy.Qsymia is significantly more expensive than phentermine-only pills, costing about $200 per month without insurance. The combined pill has a long list of potential side effects, including severe birth defects if taken while pregnant. This is a newer medication (FDA approval in 2012), so long-term side effects remain relatively unknown. Summary.diarrhea. dry mouth and tongue. bad taste in your mouth. constipation*. headaches*. mild allergic reaction *†. * To learn more about this side effect, see the “Side effects explained ...What Is Wegovy? Wegovy (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e ...Oct 26, 2022 · Common Qsymia side effects may include: joint pain, ankle sprain; flu-like symptoms; dizziness; constipation; numbness or tingly feeling; sleep problems (insomnia); dry mouth, changes in your sense of taste; or. mood changes, feelings of low self-worth, loss of interest in things you once enjoyed, ... Now, semaglutide (under the brand name Wegovy) is FDA approved for weight loss. It can be used by adults with a body mass index (BMI) greater than or equal to 30 mg/kg² alone or 27 mg/kg² with at least one weight-related condition (e.g., high blood pressure, high cholesterol, Type 2 diabetes). Semaglutide is also approved for chronic weight ...Jun 28, 2023 · Symptoms of severe phentermine side effects include ( 3 , 4 ): Chest pain. Pounding or irregular heartbeat, or fluttering in your chest. Lightheadedness or faintness. Shortness of breath, even with only mild exertion. Swelling in your legs, ankles, or feet (edema) Slurred speech or weakness on one side of your body. The highest dose of Qsymia contains only 15mg of Phentermine, but the average dose of Phentermine (for weight loss when used by itself) is 37.5mg. While it may be nice to have a combination medication, it may actually be better to prescribe both medications individually so you have more control over the dosages of each medication.Jun 28, 2023 · Symptoms of severe phentermine side effects include ( 3 , 4 ): Chest pain. Pounding or irregular heartbeat, or fluttering in your chest. Lightheadedness or faintness. Shortness of breath, even with only mild exertion. Swelling in your legs, ankles, or feet (edema) Slurred speech or weakness on one side of your body. Qsymia has an average rating of 7.7 out of 10 from a total of 564 reviews on Drugs.com. 71% of reviewers reported a positive experience, while 15% reported a negative experience. Condition.Adults Adverse reactions occurring at greater than or equal to 5% and at least 1.5 times placebo in adults include paraesthesia, dizziness, dysgeusia, insomnia, constipation, and dry mouth. Adverse reactions reported in greater than or equal to 2% of QSYMIA-treated adults and more frequently than in the placebo group are shown in Table 3. Table 3.Adults Adverse reactions occurring at greater than or equal to 5% and at least 1.5 times placebo in adults include paraesthesia, dizziness, dysgeusia, insomnia, constipation, and dry mouth. Adverse reactions reported in greater than or equal to 2% of QSYMIA-treated adults and more frequently than in the placebo group are shown in Table 3. Table 3.The latest weight loss drugs work in a new way to help you shed pounds with minimal side effects. Learn how they do it and why you take them long term. ... (Qsymia®): This medication also ...The table below lists prescription drugs approved by the FDA for weight loss. The FDA has approved five of these drugs—orlistat (Xenical, Alli), phentermine-topiramate (Qsymia), naltrexone-bupropion (Contrave), liraglutide (Saxenda), and semaglutide (Wegovy)—for long-term use.In clinical studies, patients lost the most weight after taking Contrave for 36 weeks and maintained weight loss through 56 weeks. In terms of phentermine weight loss, studies were only done for a short period of time. Once you stop phentermine, your appetite will return to normal. As a result, weight gain may occur.The table below lists prescription drugs approved by the FDA for weight loss. The FDA has approved five of these drugs—orlistat (Xenical, Alli), phentermine-topiramate (Qsymia), naltrexone-bupropion (Contrave), liraglutide (Saxenda), and semaglutide (Wegovy)—for long-term use. Mar 22, 2019 · An inexpensive weight-loss drug approved 60 years ago for only short-term use also may be safe and effective for longer-term treatment, according to a study conducted by researchers at Wake Forest ... Aug 17, 2019 · 1. In 2012, a new medication called Qsymia (with both Adipex and Topamax components) became available for weight loss. It was the first FDA approved weight loss drug in its class. The weight loss pill is a combination of 2 existing drugs: phentermine and topiramate. This combination has been shown to be a good tool for weight loss in addition ... Mar 13, 2023 · weight loss. impaired taste (changes in how things taste) trouble with memory. More common side effects in people taking Topamax for epilepsy include: tingling in the legs and arms. loss of ... Common side effects of Xenical include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules. Side effects include: Oily spotting ...Mar 9, 2020 · However, the EMA has not approved this medication due to its abuse potential, the lack of long-term data on the cardiovascular effects of phentermine, and the cognitive side effects of topiramate—attention, language, and memory impairment . As this drug combination contains phentermine, it is a controlled DEA schedule IV substance. Qsymia may affect how you think and cause confusion, problems with concentration, attention, memory or speech. Tell your healthcare provider if symptoms occur. Slowing of growth. Qsymia may slow the increase in height in children 12 years and older. Increases of acid in bloodstream (metabolic acidosis).Jan 6, 2021 · During the last few decades, some anti-obesity drugs were used to treat morbid obesity; however, many of them were removed from the market owing to long-term side effects, particularly cardiovascular issues . Since then, anti-obesity drug development process focusses on both weight loss efficacy and cardiovascular safety. The latest weight loss drugs work in a new way to help you shed pounds with minimal side effects. Learn how they do it and why you take them long term. ... (Qsymia®): This medication also ...Aug 3, 2023 · What Is Wegovy? Wegovy (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e ... Side Effects of Qsymia. Side effects of Qsymia in patients taking it for up to one year were paraesthesia (tingling or pins-and-needles sensations most often in the hands, feet, or face), dizziness, dysgeusia (distortion of the sense of taste), insomnia, constipation, and dry mouth. This medication can cause a mild (2 bpm) increase in resting ...Objective: The aim of this work was to study weight loss and risk of cardiovascular disease (CVD) or death associated with longer-term phentermine use. Methods: Using electronic health record data, 13,972 adults were identified with a first phentermine fill in 2010 to 2015, creating exposure categories according to a patient's duration of use (referent: ≤ 3 months).Jan 6, 2021 · During the last few decades, some anti-obesity drugs were used to treat morbid obesity; however, many of them were removed from the market owing to long-term side effects, particularly cardiovascular issues . Since then, anti-obesity drug development process focusses on both weight loss efficacy and cardiovascular safety. Feb 14, 2023 · Common side effects of Xenical include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules. Side effects include: Oily spotting ... The options have short-term side effects and long-term risks. However, when other weight loss medications and diets have not produced adequate results, doctors may consider surgery.Side Effects of Qsymia. Side effects of Qsymia in patients taking it for up to one year were paraesthesia (tingling or pins-and-needles sensations most often in the hands, feet, or face), dizziness, dysgeusia (distortion of the sense of taste), insomnia, constipation, and dry mouth. This medication can cause a mild (2 bpm) increase in resting ...Side Effects of Qsymia. Side effects of Qsymia in patients taking it for up to one year were paraesthesia (tingling or pins-and-needles sensations most often in the hands, feet, or face), dizziness, dysgeusia (distortion of the sense of taste), insomnia, constipation, and dry mouth. This medication can cause a mild (2 bpm) increase in resting ...Oct 27, 2021 · Introduction. The worldwide prevalence of overweight and obesity, defined as having a body mass index (BMI) between 25.0–29.9 kg/m 2 and ≥30.0 kg/m 2, 1 has almost tripled since the 1970s, with nearly 40% of adults being overweight and 13% obese, and these numbers have been steadily increasing. 2 Patients with obesity are at an increased risk of developing comorbidities such as ... Mar 22, 2019 · An inexpensive weight-loss drug approved 60 years ago for only short-term use also may be safe and effective for longer-term treatment, according to a study conducted by researchers at Wake Forest ... tiredness and weakness. trouble thinking, speaking, or walking. upper right abdominal or stomach pain. weak or feeble pulse. weight gain. yellow eyes or skin. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.May 8, 2023 · In clinical studies, patients lost the most weight after taking Contrave for 36 weeks and maintained weight loss through 56 weeks. In terms of phentermine weight loss, studies were only done for a short period of time. Once you stop phentermine, your appetite will return to normal. As a result, weight gain may occur. Tardive dyskinesia is a movement disorder that is a side effect of medications, especially first-generation antipsychotics. Less common causes are second-generation antipsychotics, antidepressants, mood stabilizers, antiepileptic drugs, movement disorder medications, antiemetics, and decongestants. Two medications have been approved to treat ...This review showed that combining low doses of phentermine and topiramate for the treatment of obesity minimized side effects while maintained weight loss efficacy. The side effects were paraesthesia, taste changes and dry mouth. Weight loss induced by the combination was associated with improved BP through one and two years of treatment.This combination consists of fixed lower doses of phentermine and topiramate (3.75/23, 7/46, 11.25/69 and 15/92 mg) and is available in capsules under the brand name Qsymia. Common side effects of phentermine include nervousness, excitability, insomnia, headache, dry mouth, sweating, tachycardia, palpitations, nausea, constipation, and thirst.

Aug 1, 2023 · tiredness and weakness. trouble thinking, speaking, or walking. upper right abdominal or stomach pain. weak or feeble pulse. weight gain. yellow eyes or skin. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. . Jimbo jumbopercent27s

1. Nausea and vomiting. Nausea is the most common semaglutide side effect. Up to 20% of people taking it for Type 2 diabetes reported nausea in clinical trials. Nausea is even more common if you’re taking the higher-dose version for weight loss. Vomiting tends to be less common than nausea.Topamax withdrawal can occur when it’s stopped abruptly instead of tapered. The greatest risk is that your seizures worsen. Instead of stopping Topamax at once, your HCP can help you taper your dosage gradually. 7. Gabapentin (Neurontin) Gabapentin (Neurontin) is FDA-approved to treat seizures and nerve pain.Topamax withdrawal can occur when it’s stopped abruptly instead of tapered. The greatest risk is that your seizures worsen. Instead of stopping Topamax at once, your HCP can help you taper your dosage gradually. 7. Gabapentin (Neurontin) Gabapentin (Neurontin) is FDA-approved to treat seizures and nerve pain.Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. It can help weight loss by making you less hungry. Or it can help you feel full longer. Phentermine also is offered combined with topiramate for weight loss (Qsymia). The combined drug is approved for long-term use.May 4, 2023 · How Long Will Phentermine Last. This drug’s side effects are mild, including fatigue, dizziness, headache, restlessness, nervousness, impotence, sleepiness, and nausea. Phentermine is generally prescribed by doctors and used for depression that is not responding to other treatments. The drug is also used as a weight-loss aid. Qsymia's results have been clinically tested in two long-term studies with ... QSYMIA CAN CAUSE SERIOUS SIDE EFFECTS, INCLUDING: Birth defects (cleft lip/cleft palate). If you take Qsymia during ... Side effects Interactions FAQ What is Qsymia? Qsymia contains a combination of phentermine and topiramate in an extended-release capsule. Phentermine is an appetite suppressant similar to an amphetamine. Topiramate is typically used as a seizure medication, also called an anticonvulsant.1. In 2012, a new medication called Qsymia (with both Adipex and Topamax components) became available for weight loss. It was the first FDA approved weight loss drug in its class. The weight loss pill is a combination of 2 existing drugs: phentermine and topiramate. This combination has been shown to be a good tool for weight loss in addition ...What Are Side Effects of Qsymia? Side effects of Qsymia can include: mood changes such as depression, trouble sleeping (insomnia), confusion, dizziness, anxiety, tiredness, irritability, constipation, numbness or tingly feeling, altered sense of taste, dry mouth, unpleasant taste in your mouth, headache, upper respiratory tract infection,The combination of phentermine and extended-release topiramate (Qsymia) was approved by the FDA in July 2012 as an adjunct to a reduced-calorie diet and exercise for long-term weight management in individuals with an initial BMI of 30 kg/m 2 or higher (obese) or 27 kg/m 2 or higher (overweight) with at least one weight-related comorbid ...Long-term users may also experience unwanted long-term side effects resulting from changes to physiology and neurobiology that accumulate over an extended period of time. Individual Factors Hypothetically, two individuals may commence Qsymia treatment on the same day, at the same dose, and avoid using co-administered substances.Studies show that on average, people taking Topamax lose around 11 lbs. Higher doses and longer duration of use generally result in more weight loss. The most common side effects associated with Topamax for weight loss are abnormal skin sensations (like burning, tingling, numbness), altered sense of taste, and slowed thinking and movements.Objective: The aim of this work was to study weight loss and risk of cardiovascular disease (CVD) or death associated with longer-term phentermine use. Methods: Using electronic health record data, 13,972 adults were identified with a first phentermine fill in 2010 to 2015, creating exposure categories according to a patient's duration of use (referent: ≤ 3 months).In clinical studies, phentermine-topiramate reduced body weight by 8.6% to 9.4% more than placebo using a conservative ITT analysis.108. Phentermine-topiramate carries risks of several serious side effects. Notably, topiramate is a recognized teratogen, at least at the higher doses used for the treatment of epilepsy.Qsymia has an average rating of 7.7 out of 10 from a total of 564 reviews on Drugs.com. 71% of reviewers reported a positive experience, while 15% reported a negative experience. Condition.Qsymia (phentermine and topiramate) is a weight loss medication used to help people who are overweight or obese, along with diet and exercise, to lose weight and keep the weight off. Common side effects of Qsymia include sensations of pricking, burning, tingling, or numbness of the skin; dizziness, blurred vision, fatigue, indigestion, urinary tract infections (UTIs), headache, nausea, back ... Long-term users may also experience unwanted long-term side effects resulting from changes to physiology and neurobiology that accumulate over an extended period of time. Individual Factors Hypothetically, two individuals may commence Qsymia treatment on the same day, at the same dose, and avoid using co-administered substances..

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